Engineering the Future

in targeted cancer therapy

ImmuVia is developing novel antibody-based targeted therapeutics to treat oncological diseases.

Enhanced antibody diagram

Anti-MUC16 Humanized IgG1

Binds to MUC16 Tumor Antigen

Anti-DR5 Fully Human scFv

Binds to Death Receptor 5

Targeting tumors with high unmet medical need

Our aim is to improve efficacy, while avoiding toxicity

1

Our agents are designed to eradicate tumors effectively & selectively – not harming healthy tissues

2

Unlike conventional chemotherapeutic agents and antibody-drug conjugates, ImmuVia discovers and develops new medicines that do not contain compounds that are toxic for the patients

3

Unlike immuno-oncology treatments, which often provoke patients' immune system to cause side effects, ImmuVia's agents do not interfere with the immune system

4

ImmuVia uses its hard-won insights to develop innovative biologics

Selective Targeting Technology

Flagship Drug Candidate IMV-M™

Two arms recognize a cancer cell via a tumor-associated antigen, MUC16

Multiple IMV-M™ molecules bind to a single MUC16

Two arms target death receptor 5 (DR5)

MUC16 clustering enforces clustering of DR5

Clustering triggers DR5 activation, initiating apoptosis (programmed cell death)

Selective Targeting Technology: Universal

Building on the discovery of IMV-M™, ImmuVia developed a universal selective targeting platform that creates recombinant antibody-based agents

These agents bind to a clinically validated tumor-associated antigen and powerfully trigger apoptosis—selectively and effectively—in target cells

Our Science

Leveraging decades of experience, our team has identified high-value targets and developed biologic agents for effective eradiation of malignant cells.

TARGETING

Targets are present in high density on cancer cells
Not present on most normal cells

ANTIBODIES

Recombinant antibody-based proteins
Induce self-destruction of targeted cells

BREAKTHROUGH

Innovative mode of tumor eradication
Novel approach to cancer treatment

POTENCY

Unlike ADCs, our molecules do not rely on internalization inside cells
No reliance on intoxication of cells - thus can kill drug-resistant cells

MANUFACTURING

Compatible with standard antibody manufacturing processes
No chemical modification of the protein is involved

NOT TOXIC

No toxic chemicals or proteins
No recruitment of immune cells, which could cause dangerous side effects